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Genetic polymorphism of apolipoprotein H (β 2 ‐glycoprotein I) in African blacks from the Ivory Coast
Author(s) -
Cleve Hartwig,
Vogt Ulrike,
Ilyas Kamboh M.
Publication year - 1992
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.11501301185
Subject(s) - isoelectric focusing , apolipoprotein b , negroid , allele , biology , polymorphism (computer science) , population , allele frequency , genetics , microbiology and biotechnology , gene , biochemistry , medicine , cholesterol , enzyme , environmental health
The apolipoprotein H (APO H) polymorphism was analyzed in the Negroid population from the Ivory Coast using polyacrylamide gel isoelectric focusing, followed by immunoblotting. The gene frequencies of alleles APO H*1, APO H*2, APO H*3 and APO H*4 were calculated to be 0.012, 0.921, 0.047 and 0.020, respectively. The assumption that APO H*4 represents a Negroid marker allele is supported by this population study.