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Application of capillary electrophoresis in peptide research
Author(s) -
Yildiz Eraslan,
Grübler Gerald,
Hörger Susanne,
Zimmermann Hans,
Echner Hartmut,
Stoeva Stanka,
Voelter Wolfgang
Publication year - 1992
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.11501301145
Subject(s) - capillary electrophoresis , chromatography , peptide , electrophoresis , chemistry , capillary action , materials science , biochemistry , composite material
Comparison of high performance liquid chromatograms (HPLC) with capillary electrophoresis shows the latter to be superior in many cases owing to rapid separation, high resolution and high sensitivity. This is demonstrated with two examples (i) the isolation of natural peptides from bovine tissue and (ii) characterization of a synthetic peptide mixture with the natural sequence (fragment) of the human immunodeficiency virus (HIV) transmembrane glycoprotein gp 41 env.