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Separation of human alloalbumain variants by isoelectric focusing
Author(s) -
Rocha Jorge,
Kömpf Jost,
Ferrand Nuno,
Amorim António,
Ritter Horst
Publication year - 1991
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.1150120415
Subject(s) - isoelectric focusing , locus (genetics) , chromatography , human plasma , human albumin , chemistry , albumin , biochemistry , gene , enzyme
A technique for the separation of human alloalbumin variants by means of isoelectric focusing in the presence of 8 M urea and 60 m M L ‐serine is described. The potential usefulness of this technique in the detection and classification of genetic heterogeneity at the albumin locus is demonstrated by the differentiation of three human alloalbumin variants of European origin.