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Searching for genetic markers for hereditary diseases in cattle by means of DNA fingerprinting
Author(s) -
Doff Gaudenz,
Glowatzki MarieLouise,
Gaillard Claude
Publication year - 1991
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.1150120204
Subject(s) - microsatellite , genetic marker , biology , genetics , dna profiling , polymerase chain reaction , hereditary diseases , computational biology , dna , allele , gene
Losses caused by inherited diseases affect not only the breeder's income but also the breeding programs themselves. In Switzerland the cardiomyopathy of cattle and the syndrome of arachnomelia and arthrogryposis are currently being investigated in order to find genetic markers for these diseases. It seems that DNA fingerprinting with multilocus probes is the most efficient approach available at present. Microsatellites analyzed with the polymerase chain reaction technique will provide a usable, marker map within the next ten years and will therefore provide a perfect tool to find markers for hereditary diseases.