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The genetic haptoglobin polymorphism: Relevance of paternity assessment
Author(s) -
Patzelt Dieter,
Geserick Gunther,
Schröder Helga
Publication year - 1988
Publication title -
electrophoresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.666
H-Index - 158
eISSN - 1522-2683
pISSN - 0173-0835
DOI - 10.1002/elps.1150090808
Subject(s) - haptoglobin , polymorphism (computer science) , genetics , relevance (law) , biology , computational biology , allele , gene , immunology , political science , law
A practical method for haptoglobin subtyping is described utilizing fast sample preparation by means of batch adsorption to DEAE‐cellulose and subsequent isoelectric focusing of reductively cleaved samples. The expanded haptoglobin polymorphism leads to an increase of the theoretical paternity exclusion rate to approximately 33 %. Hence, the system appears to be highly attractive for paternity assessment.