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Isoniazid‐sensing Behavior of a Hybrid Silsesquioxane and Cobalt Pentacyanonitrosylferrate‐based Nanocomposite
Author(s) -
Souza Magossi Mariana,
Souza Magossi Maiara,
Dias Filho Newton Luiz,
Ribeiro do Carmo Devaney
Publication year - 2021
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202100119
Subject(s) - silsesquioxane , cobalt , nanocomposite , detection limit , graphite , redox , electrode , materials science , electrochemistry , amperometry , nuclear chemistry , chemistry , nanotechnology , polymer , chromatography , composite material , metallurgy
Abstract A novel silsesquioxane and cobalt nitroprusside compound was prepared from octa(aminopropyl)silsesquioxane, resulting in a nanocomposite (ACCoN), which was then characterized by different spectroscopic techniques. The cyclic voltammograms of the ACCoN‐modified graphite paste electrode indicated a redox pair with a formal potential (E θ′ )=0.38 V, assigned to the Co (II) Fe (II) (CN) 5 NO/Co (II) Fe (III) (CN) 5 NO redox couple. The ACCoN‐modified graphite paste electrode was sensitive to isoniazid concentrations, presenting a linear response at a concentration range from 6.0×10 −7 to 1.0×10 −5  mol L −1 , with limit of detection and amperometric sensitivity of 5.53×10 −7  mol L −1 and 0.17 A/mol L −1 , respectively.

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