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Electroanalytical Investigation and Simultaneous Determination of Etodolac and Thiocolchicoside at a Non‐modified Glassy Carbon Electrode in Anionic Surfactant Media
Author(s) -
Selcuk Ozge,
Erkmen Cem,
BozalPalabiyik Burcin,
Uslu Bengi
Publication year - 2021
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202060623
Subject(s) - etodolac , chemistry , chromatography , sodium dodecyl sulfate , differential pulse voltammetry , voltammetry , electrode , cyclic voltammetry , electrochemistry , biochemistry
In this study, a differential pulse voltammetry method was designed for the simultaneous determination of etodolac and thiocolchicoside in a tablet dosage form. This method is a sensitive, costless and reproducible one initially designed for the simultaneous determination of etodolac and thiocolchicoside using bare/unmodified glassy carbon electrode in the presence of sodium dodecyl sulfate. At optimized conditions, the method showed linear responses with etodolac and thiocolchicoside concentration in the range of 1 μM to 80 μM. The limits of detection and quantification were calculated as 0.11 μM and 0.38 μM for etodolac and 0.20 μM and 0.67 μM for thiocolchicoside, respectively.