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A Facile Fabrication of Poly‐ethionine Film on Glassy Carbon Electrode for Simultaneous and Sensitive Detection of Dopamine and Paracetamol
Author(s) -
Kannan Ayyadurai,
Manojkumar Seenivasan,
Radhakrishnan Sivaprakasam
Publication year - 2021
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202060451
Subject(s) - electrode , ethionine , dielectric spectroscopy , materials science , glassy carbon , electrochemistry , cyclic voltammetry , electrocatalyst , electrochemical gas sensor , amperometry , nuclear chemistry , analytical chemistry (journal) , chemical engineering , chemistry , chromatography , biochemistry , amino acid , methionine , engineering
An electrochemical sensor based on poly‐ethionine (Poly‐ET) film modified glassy carbon electrode was developed for sensitive and simultaneous sensing of dopamine (DA) and paracetamol (PA). The electropolymerization of ethionine monomer was carried out to modify the electrode. The modified electrode was characterized by using scanning electron microscopy, cyclic voltammetry and electrochemical impedance spectroscopy. The Poly‐ET/GCE exhibited excellent electrocatalysis towards the sensing of DA and PA. Poly‐ET/GCE showed a linear increase of current response with increase concentration of DA and PA ranging from 0.1 μM–60 μM and 0.1 μM–180 μM, respectively. The LODs were found to be 7 nM and 18 nM (S/N=3) for DA and PA, respectively. This electrochemical sensor was successfully utilized for the detection of DA and PA in pharmaceutical samples.