Premium
Zn Nanoparticles Modified Screen Printed Carbon Electrode as a Promising Sensor for Insulin Determination
Author(s) -
Šišoláková Ivana,
Hovancová Jana,
Chovancová Frederika,
Oriňaková Renáta,
Maskaľová Iveta,
Oriňak Andrej,
Radoňak Jozef
Publication year - 2021
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202060417
Subject(s) - detection limit , electrode , carbon nanotube , nanoparticle , selectivity , electrochemistry , linear range , materials science , zinc , chitosan , deposition (geology) , carbon fibers , insulin , nanotechnology , chemical engineering , inorganic chemistry , chemistry , chromatography , catalysis , organic chemistry , composite number , metallurgy , composite material , medicine , paleontology , engineering , endocrinology , sediment , biology
Screen printed carbon electrodes (SPCEs) modified by a combination of chitosan, multi walled carbon nanotubes (MWCNTs) and zinc nanoparticles (ZnNPs) were studied for the first time as a suitable candidate for non‐enzymatic insulin determination. In an effort to find the most suitable modification for electrochemical insulin determination, the stability, analytical characteristics, and selectivity were determined. The results confirmed that the ZnNPs/chitosan‐MWCNTs prepared with the Zn deposition time of 45 s displayed the best electrocatalytic activity towards insulin oxidation in a wide linear concentration range (0.5 μM to 5 μM), with low limit of detection and high sensitivity.