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Ready to Use Electrochemical Sensor Strip for Point‐of‐Care Monitoring of Serum Lithium
Author(s) -
Singh Urvasini,
Kumbhat Sunita
Publication year - 2021
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202060393
Subject(s) - lithium (medication) , electrochemistry , electrode , monolayer , point of care , electrochemical gas sensor , adsorption , materials science , potassium , inorganic chemistry , chemistry , nanotechnology , organic chemistry , medicine , nursing , endocrinology
Looking to the toxicity quotient of lithium for human well being, a simple electrochemical sensor based on self assembled monolayer with physically adsorbed 6,6’‐dibenzyl‐14‐crown‐4 ether onto a screen printed gold sensor electrode is proposed, where changein voltammetric current signal of redox probe as a mediator, is the basis of transducer. The sensor is responsive to 0.1 mM to 2.5 mM lithium and selective over potassium, calcium and large excess of sodium in solution. The system is promising for real‐time selective recognition of lithium in a label free assay and for point‐of‐care lithium level monitoring in clinical and biomedical fields.