Premium
Fabrication of a Gold Dual‐microelectrode Patterned on a Silicone Substrate Probe for the Discrimination of Different Tissues
Author(s) -
Ugwah Justina A.,
Savage Niall,
Messina Walter,
Donnell Brian D. O.,
O'Sullivan Martin J.,
Moore Eric J.
Publication year - 2021
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202060339
Subject(s) - microelectrode , multielectrode array , materials science , substrate (aquarium) , biomedical engineering , fabrication , silicone , nanotechnology , electrical impedance , electrode , chemistry , pathology , medicine , electrical engineering , composite material , alternative medicine , oceanography , engineering , geology
A gold dual‐microelectrode probe patterned on a silicon substrate for bio‐impedance measurement was fabricated, characterised and tested on different types of tissues. The aim of this study is to fabricate a device capable of using bioimpedance to discriminate different tissue types. This proof of concept of the device was characterised on meat and a gel/lard phantom which mimics fat and muscle. The initial results demonstrated that the gold dual‐microelectrode probe had excellent electrochemical recording potential. The bio‐impedance data derived was capable of differentiation between biological tissues. Bio‐impedance measurement may enhance cancer diagnostics by providing novel data in relation to cancer and surrounding healthy tissue. This manuscript describes the design, fabrication and validation of a gold dual‐microelectrode bioimpedance sensor with a potential future application in cancer diagnostics.