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Determination of Chlorpromazine Hydrochloride with a Layered Double Hydroxide Modified Glassy Carbon Electrode as a Nanocatalyst
Author(s) -
Jaberi Seyedeh Yasaman Shajaripour,
Ghaffarinejad Ali,
Kamalifar Mohsen,
Heidari Mozhgan
Publication year - 2020
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202060011
Subject(s) - detection limit , ascorbic acid , electrode , hydroxide , glassy carbon , chemistry , inorganic chemistry , nuclear chemistry , electrochemistry , chromatography , cyclic voltammetry , food science
We report a simple and sensitive voltammetric sensor for the determination of chlorpromazine (CPZ) based on Ni−Al layered double hydroxide (NiAlLDH) modified glassy carbon electrode (GCE). NiAlLDH was simply electrodeposited on GCE surface in a very short time. The response linear range was 1×10 −3 –1×10 −9 mol L −1 , with a detection limit of 1×10 −9 mol L −1 . The NiAlLDH film showed well defined and well separate peaks for dopamine, ascorbic acid, uric acid and CPZ in the same solution. The proposed electrode was used to measure the active pharmaceutical ingredient of CPZ tablet as a real sample.