Premium
Porous Molybdenum Carbide Nanostructured Catalyst toward Highly Sensitive Biomimetic Sensing of H 2 O 2
Author(s) -
Li Juan,
Tang Chun,
Liang Taotao,
Tang Chuyue,
Lv Xiaohui,
Tang Kanglai,
Li Chang Ming
Publication year - 2020
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.202000008
Subject(s) - materials science , catalysis , molybdenum , detection limit , porosity , nanotechnology , biosensor , chemical engineering , substrate (aquarium) , nanostructure , carbide , carbon fibers , nanocrystal , composite number , chemistry , organic chemistry , metallurgy , chromatography , composite material , engineering , oceanography , geology
There are great challenges to fabricate a highly selective and sensitive enzyme‐free biomimetic sensor. Herein for the first time a unique nanostructure of porous molybdenum carbide impregnated in N‐doped carbon (p‐Mo 2 C/NC) is synthesized by using SiO 2 nanocrystals‐templating method and is further used as an enzyme‐free electrochemical biosensor toward highly selective, sensitive detection of H 2 O 2 , of which the limit of detection, dynamic detection range and sensitivity accomplish as 0.22 μM, 0.05–4.5 mM and 577.14 μA mM −1 cm −2 , respectively, and are much superior to the non‐porous molybdenum carbide impregnated in N‐doped carbon (Mo 2 C/NC). The sensor is also used to monitor H 2 O 2 released from A549 living cells. This work holds a great promise to be used to monitor the presence of H 2 O 2 in biological research while offering an important knowledge to design a highly selective and sensitive biomimetic sensor by synthesizing a porous catalyst to greatly improve the reaction surface area rather than conventionally only relying on dispersing the catalyst material into porous carbon substrate.