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Smartphone‐coupled Electrochemical Analysis of Cellular Superoxide Anions Based on Mn x (PO 4 ) y Monolayer Modified Porous Carbon
Author(s) -
Cai Xuan,
Gao Qianmei,
Zuo Shaohua,
Zhao Hongli,
Lan Minbo
Publication year - 2020
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201900623
Subject(s) - chronoamperometry , cyclic voltammetry , electrochemistry , monolayer , electrochemical gas sensor , materials science , analytical chemistry (journal) , electrode , potentiostat , nanotechnology , chemistry , chromatography
Here we established a palm‐sized electrochemical sensor for the determination of cell‐released superoxide anions (O 2 .− ) based on a self‐developed portable potentiostat (xenSTAT) which can perform fast analysis with visual real‐time data and customizable parameters. The xenSTAT was equipped with Bluetooth and USB interfaces, thus being able to be connected with both smartphones and computers for electrochemical analysis. A novel Nanozyme based on Mn x (PO 4 ) y monolayer modified porous carbon cubic was synthesized and used as functional material on the surface of working electrode. By using cyclic voltammetry (CV) and chronoamperometry, xenSTAT was demonstrated to exhibit satisfying sensitivity and excellent stability for real‐time monitoring of O 2 .− released from cancer cells. With decreased cost, customizable development, small size and convenient usage, the xenSTAT described in this work could promote the commercialization and widespread of in‐house built electrochemical sensors for the monitoring of O 2 .− in the future.