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Enhanced Electrocatalytic Activity of Ni‐CNT Nanocomposites for Simultaneous Determination of Epinephrine and Dopamine
Author(s) -
Manivel Perumal,
Thamilselvan Annadurai,
Rajagopal Venkatachalam,
Nesakumar Noel,
Suryanarayanan Vembu
Publication year - 2019
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201900201
Subject(s) - amperometry , ascorbic acid , differential pulse voltammetry , detection limit , electrode , electrochemical gas sensor , carbon nanotube , electrochemistry , nanocomposite , cyclic voltammetry , materials science , chemistry , nuclear chemistry , chromatography , nanotechnology , food science
A promising electrochemical sensor based nickel‐carbon nanotube (Ni‐CNT) modified on glassy carbon (GC) electrode had been developed and the properties of the modified electrode were characterized by multispectroscopic analysis. The fabricated sensor (GC/Ni‐CNT) electrode was utilized to determine the catecholamines such as epinephrine and dopamine simultaneously. Differential pulse voltammetry and amperometry were used to verify the electrochemical behavior of the studied compounds. The GC/Ni‐CNT based amperometric sensor showed a wide linear range and low detection limit with high analytical sensitivity of 8.31 and 6.61 μA μM −1 for EP and DA, respectively which demonstrates better characteristics compared to other electrodes reported in the literature. Further, no significant change in amperometric current response was observed in presence of biological interference species such as glucose, cysteine, citric acid, uric acid and ascorbic acid in the detection of EP and DA. The utility of this GC/Ni‐CNT electrode was well established for the determination of EP and DA in human urine samples.