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3D‐printed Portable Platform for Mechanized Handling and Injection of Microvolumes Coupled to Electrochemical Detection
Author(s) -
Mendonça Dianderson M. H.,
Rocha Diego P.,
Dutra Gustavo S. V.,
Cardoso Rafael M.,
Batista Alex D.,
Richter Eduardo M.,
Munoz Rodrigo A. A.
Publication year - 2019
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201800834
Subject(s) - amperometry , analyte , electrochemistry , 3d printing , chemistry , electrode , materials science , nanotechnology , chromatography , metallurgy
We present a low‐cost mechanized system fabricated using fused deposition modelling 3D‐printing technology to manipulate microvolumes and perform injections on an electrochemical cell in wall‐jet configuration. As a proof‐of‐concept, the amperometric detection of paracetamol (model analyte) on a screen‐printed electrode using 0.5 μL aliquots resulted in highly reproducible responses (RSD <3 %). Moreover, handling of microliter aliquots of butylhydroxytoluene (phenolic antioxidant) and 2,2‐diphenyl‐2‐picrylhydrazyl (DPPH) to promote the radical‐scavenging reaction to determine antioxidant capacity by electrochemical detection of residual DPPH was demonstrated (time‐controlled reaction). A final application of the system was devoted to the analysis of cocaine and a common adulterant found in seized samples. The mechanized 3D‐printed analytical platform is capable to execute diverse sample preparation steps on board by handling microliter aliquots and subsequent electrochemical detection. 3D‐printing technology enabled the fabrication of a versatile and low‐cost (