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The Synthesis of Functional Cobalt Oxide Nanostructures, and their Sensitive Glucose Sensing Application
Author(s) -
Ibupoto Zafar Hussain,
Tahira Aneela,
Mallah Arfana Begum,
Shahzad Sohail Anjum,
Willander Magnus,
Wang Bin,
Yu Cong
Publication year - 2017
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201600286
Subject(s) - cobalt oxide , high resolution transmission electron microscopy , cobalt , materials science , nanostructure , transmission electron microscopy , oxide , detection limit , biosensor , nuclear chemistry , inorganic chemistry , nanotechnology , chemistry , chromatography , metallurgy
In this study, a novel approach is adapted for the synthesis of new nanostructures of cobalt oxide (Co 3 O 4 ) by low temperature aqueous chemical growth method in the presence of water soluble amino acids such as L‐arginine, L‐aspartic acid, L‐isoleucine, L‐leucine, L‐serine and L‐threonine. The synthesized nanostructures were characterized by X‐ray diffraction (XRD), scanning electron microscopy (SEM) and high resolution transmission electron microscopy (HRTEM). The nanostructures exhibit well defined morphology and are of high purity. To explore the potential application of the prepared nanostructures of cobalt oxide, the non‐enzymatic glucose sensor is developed by modifying the glassy carbon electrode. Serine assisted cobalt oxide nanostructures showed excellent sensitivity of 4169.00 μA/mM cm 2 , wide linear range of 0.01 mM to 20 mM and detection limit was estimated as 0.001 mM (S/N=3). The analytical parameters for the serine assisted cobalt oxide nanostructures based glucose sensor were evaluated and it was found that the sensor is highly selective, reproducible, repeatable, reversible, and stable. Finally, the practical application of the serine assisted cobalt oxide nanostructures based glucose sensor was examined by measuring the glucose concentrations from real human blood samples.