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A Two‐step Anodic Thiocyanation of Alkenes in Formic Acid
Author(s) -
Gitkis Anna,
Becker James Y.
Publication year - 2016
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201600197
Subject(s) - formic acid , alkene , chemistry , thiocyanate , formate , allylic rearrangement , medicinal chemistry , organic chemistry , inorganic chemistry , catalysis
Initial formation of thiocyanogen [(SCN) 2 ] by controlled potential anodic oxidation of NH 4 SCN in formic acid‐LiClO 4 followed by addition of alkene as a second step, has been investigated for eight alkene derivatives. The results indicate that major products from most of the alkenes studied are addition products involving thiocyanate and formate groups. Also minor products of addition of isothiocyanate and thiocyanate groups, and allylic thiocyanates as substitution derivatives, were formed.