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Graphene Oxide/ZnO Nano Composite for Sensitive and Selective Electrochemical Sensing of Levodopa and Tyrosine Using Modified Graphite Screen Printed Electrode
Author(s) -
Beitollahi Hadi,
Garkani Nejad Fariba
Publication year - 2016
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201600143
Subject(s) - nanorod , graphene , materials science , electrode , graphite oxide , electrochemical gas sensor , graphite , composite number , electrochemistry , oxide , nanotechnology , nano , selectivity , chemistry , composite material , organic chemistry , metallurgy , catalysis
Determination of levodopa and tyrosine as two important species for treatment of Parkinson's disease is described. A novel electrochemical sensor involving graphene oxide/ZnO nanorods (GR/ZnO) nano composite and the graphite screen‐printed electrodes (GSPE) was developed for the simultaneous detection of levodopa and tyrosine. The screen‐printed electrodes with several advantages, including low cost, versatility and miniaturization were employed. On the other hand, the graphene oxide/ZnO nanorods nano composite was casted on the surface of GSPE to obtain GR/ZnO/SPE. The proposed nano sensor has excellent performance such as high sensitivity, good selectivity and analytical application in real samples. The combination of graphene oxide/ZnO nanorods nano composite with the screen‐printed electrode is favorable for amplifying electrochemical signals. Under optimized conditions square wave voltammetry (SWV) exhibited linear dynamic ranges from 1.0×10 −6 to 1.0×10 −3 M and 1.0×10 −6 to 8.0×10 −4 M with detection limits of 4.5×10 −7 M and 3.4×10 −7 M for levodopa and tyrosine respectively.