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Determination of Total PSA Using Magnetic Beads and a Re‐usable Screen Printed Carbon Electrode Array
Author(s) -
Biscay Julien,
González García María Begoña,
García Agustín Costa
Publication year - 2015
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201500351
Subject(s) - usable , detection limit , electrode , linear range , electrochemistry , materials science , chromatography , analytical chemistry (journal) , chemistry , computer science , world wide web
A total PSA (tPSA) assay using magnetic beads (1 µm) and a re‐usable 8‐channel screen printed electrochemical array is here reported. The reaction scheme is based on a one step sandwich assay. The linear range obtained is comprised between 5 and 100 ng/mL of tPSA and have a limit of detection of 1.86 ng/mL. This methodology was validated, performing determination of tPSA in serum and the results were compared with a commercial ELISA kit.