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A Highly Sensitive Sensor Based on Reduced Graphene Oxide, Carbon Nanotube and a Co(II) Complex Modified Carbon Paste Electrode: Simultaneous Determination of Isoprenaline, Captopril and Tryptophan
Author(s) -
Rajabzadeh Nooshin,
Benvidi Ali,
MazloumArdakani Mohammad,
Firouzabadi Afsaneh Dehghani,
Vafazadeh Rasoul
Publication year - 2015
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201500236
Subject(s) - graphene , detection limit , carbon nanotube , oxide , cobalt , cyclic voltammetry , materials science , carbon paste electrode , redox , electrode , inorganic chemistry , chemistry , nuclear chemistry , electrochemistry , nanotechnology , chromatography , metallurgy
This paper describes the development of a reduced graphene oxide (RGO), carbon nanotube (CNT) and Co(II) complex (cobalt(II) bis (benzoylacetone) ethylenediimino) (CBE) modified carbon paste electrode (CPE) for simultaneous determination of isoprenaline (IP), captopril (CAP) and tryptophan (Try). A pair of well‐defined redox peaks of Co(II) complex were obtained through a direct electron transfer between the Co(II) complex and the CPE. The proposed sensor showed very efficient electrocatalytic activity for anodic oxidation of IP in a 0.1 M phosphate buffer solution (pH 7.0). Square wave voltammetry (SWV) exhibited two linear dynamic ranges of 0.125–30.0 µM and 30.0–300.0 µM for IP. The detection limit for IP was found to be 50 nM. The proposed sensor was successfully applied for the determination of IP in real samples such as human blood serum, urine and IP ampoule.