Electrochemical Treatment of Glassy Carbon for Label‐Free Detection of DNA Bases and Neurotransmitters

Electrochemically reduced glassy carbon ( r ‐GC) showed a superior electrochemical sensing performance, compared to oxidized GC ( ox ‐GC) and untreated GC for the oxidation of 4 DNA bases and neurotransmitters (epinephrine, norepinephrine and serotonin). r ‐GC exhibited not only the largest current intensities of all redox biomolecules, but also displayed an excellent selectivity in detecting coexisting redox biomolecules. The enhanced performance of r ‐GC was attributed to the improved surface cleanliness of electrode and its catalytic surface functional groups. The results presented herein imply that simple electrochemical treatments are a viable method to produce sensitive and selective electrodes for label‐free biosensing.