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Electrochemical Treatment of Glassy Carbon for Label‐Free Detection of DNA Bases and Neurotransmitters
Author(s) -
Zhang Yan,
Kim Doo Young
Publication year - 2015
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201500228
Subject(s) - glassy carbon , biomolecule , electrochemistry , redox , selectivity , biosensor , chemistry , electrode , combinatorial chemistry , inorganic chemistry , catalysis , organic chemistry , cyclic voltammetry , biochemistry
Abstract Electrochemically reduced glassy carbon ( r ‐GC) showed a superior electrochemical sensing performance, compared to oxidized GC ( ox ‐GC) and untreated GC for the oxidation of 4 DNA bases and neurotransmitters (epinephrine, norepinephrine and serotonin). r ‐GC exhibited not only the largest current intensities of all redox biomolecules, but also displayed an excellent selectivity in detecting coexisting redox biomolecules. The enhanced performance of r ‐GC was attributed to the improved surface cleanliness of electrode and its catalytic surface functional groups. The results presented herein imply that simple electrochemical treatments are a viable method to produce sensitive and selective electrodes for label‐free biosensing.