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Amperometric Lactate Biosensor Based on Carbon Paste Electrode Modified with Benzo[ c ]cinnoline and Multiwalled Carbon Nanotubes
Author(s) -
Çelik Ali Cihan,
Öztürk Funda,
Erden Pınar Esra,
Kaçar Ceren,
Kılıç Esma
Publication year - 2015
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201500180
Subject(s) - biosensor , cinnoline , amperometry , carbon paste electrode , detection limit , carbon nanotube , electrode , carbon fibers , glucose oxidase , chemistry , nuclear chemistry , materials science , chromatography , nanotechnology , electrochemistry , organic chemistry , cyclic voltammetry , composite material , composite number
Amperometric lactate biosensor based on a carbon paste electrode modified with benzo[ c ]cinnoline and multiwalled carbon nanotubes is reported. Incorporation of benzo[ c ]cinnoline acting as a mediator and multiwalled carbon nanotubes providing a conduction pathway to accelerate electron transfer due to their excellent conductivity into carbon paste matrix resulted in a high performance lactate biosensor. The resulting biosensor exhibited a fast response, high selectivity, good repeatability and storage stability. Under the optimal conditions, the enzyme electrode showed the detection limit of 7.0×10 −8 M with a linear range of 2.0×10 −7 M–1.1×10 −4 M. The usefulness of the biosensor was demonstrated in serum samples.