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Electrochemical Sensor for the Quantification of Dopamine Using Glassy Carbon Electrodes Modified with Single‐Wall Carbon Nanotubes Covalently Functionalized with Polylysine
Author(s) -
Gutiérrez Alejandro,
Gasnier Aurélien,
Pedano María L.,
GonzalezDominguez Jose Miguel,
AnsónCasaos Alejandro,
HernándezFerrer Javier,
Galicia Laura,
Rubianes María D.,
Martínez María T.,
Rivas Gustavo A.
Publication year - 2015
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201500053
Subject(s) - carbon nanotube , ascorbic acid , differential pulse voltammetry , polylysine , electrode , glassy carbon , dopamine , electrochemistry , materials science , voltammetry , cyclic voltammetry , chemistry , nanotechnology , organic chemistry , food science , neuroscience , biology
We report a dopamine electrochemical sensor based on the modification of glassy carbon electrodes (GCE) with polylysine‐functionalized single‐wall carbon nanotubes (SWCNT‐PLys). The resulting electrodes (GCE/SWCNT‐PLys) showed a significant improvement in the electrooxidation of dopamine with drastic decrease in the peak potentials separation and important enhancement in the associated currents. Dopamine was detected by differential pulse voltammetry‐adsorptive stripping with medium exchange at nanomolar levels even in the presence of high excess of ascorbic and uric acids. The sensor was successfully used for the quantification of dopamine in urine samples enriched with the neurotransmitter.