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Preparation, Characterization and Electrochemical Application of ZnO‐CuO Nanoplates for Voltammetric Determination of Captopril and Tryptophan Using Modified Carbon Paste Electrode
Author(s) -
Beitollahi Hadi,
Ghofrani Ivari Susan,
Alizadeh Reza,
Hosseinzadeh Rahman
Publication year - 2015
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201500016
Subject(s) - captopril , carbon paste electrode , electrode , detection limit , electrochemistry , materials science , chemistry , analytical chemistry (journal) , cyclic voltammetry , carbon fibers , inorganic chemistry , chromatography , composite number , composite material , medicine , blood pressure , radiology
2‐chlorobenzoyl ferrocene, was synthesized and used to construct a modified ZnO‐CuO nanoplates modified carbon paste electrode. The electrooxidation of captopril at the surface of the modified electrode was studied. Under the optimized conditions, the square wave voltammetric (SWV) peak current of captopril increased linearly with captopril concentration in the range of 5.0×10 −7 to 9.0×10 −4 M and detection limit of 90.0 nM was obtained for captopril. The diffusion coefficient and kinetic parameters (such as electron transfer coefficient and the heterogeneous rate constant) for captopril oxidation were also determined. The prepared modified electrode exhibits a very good resolution between the voltammetric peaks of captopril and tryptophan which makes it suitable for the detection of captopril in the presence of tryptophan in real samples.