Electroanalysis of Benazepril Hydrochloride Antihypertensive Drug Using an Ionic Liquid Crystal Modified Carbon Paste Electrode | Zendy

Galal Ahmed | Zendy; Atta Nada F. | Zendy; Azab Shereen M. | Zendy; Ibrahim Asmaa H. | Zendy

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Electroanalysis of Benazepril Hydrochloride Antihypertensive Drug Using an Ionic Liquid Crystal Modified Carbon Paste Electrode

Author(s) -

Galal Ahmed,

Atta Nada F.,

Azab Shereen M.,

Ibrahim Asmaa H.

Publication year - 2015

Publication title -

electroanalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.574

H-Index - 128

eISSN - 1521-4109

pISSN - 1040-0397

DOI - 10.1002/elan.201400652

Subject(s) - ionic liquid , benazepril , carbon paste electrode , chemistry , hexafluorophosphate , pyridinium , tetrafluoroborate , inorganic chemistry , electrode , electrochemistry , nuclear chemistry , cyclic voltammetry , organic chemistry , medicine , catalysis , blood pressure , radiology

Electroanalysis of benazepril HCl was successful using a carbon paste electrode modified with an ionic liquid crystal ( 1‐butyl‐1‐methylpiperidinium hexafluorophosphate) in presence of sodium dodecyl sulfate. The electrode performance was compared to ionic liquids (1‐ n ‐hexyl‐3‐methyl imidazolium tetrafluoroborate and 1‐butyl‐4‐methyl pyridinium tetrafluoroborate). Electrochemical determination of benazepril HCl was in the linear dynamic range of 8.89×10 −7 to 1.77×10 −5 mol L −1 (correlation coefficient 0.999) and LOD 7.17×10 −9 mol L −1 . benazepril HCl was determined using this sensor in presence of urine metabolites such as uric acid, ascorbic acid. Binary mixtures of dopamine/benazepril and amlodipine/benazepril were also determined successfully.

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