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Direct Determination of Trace Dopamine in an Ascorbic Acid Solution at a Bare Glassy Carbon Electrode Using Differential Pulse Voltammetry
Author(s) -
Sun Lijian,
Chen Jing,
Zhao Fangmin,
Liu Na,
Zhang Yingqiu,
Jia Jianbo,
Wang Jianguo
Publication year - 2015
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201400611
Subject(s) - ascorbic acid , differential pulse voltammetry , glassy carbon , chemistry , hydrogen peroxide , detection limit , electrochemistry , electrode , carbon fibers , voltammetry , inorganic chemistry , analytical chemistry (journal) , cyclic voltammetry , redox , materials science , chromatography , organic chemistry , food science , composite material , composite number
Abstract It is difficult to monitor dopamine (DA) accurately with a bare glassy carbon electrode because of the interference of ascorbic acid (AA). In this paper, a method for the determination of DA in an AA solution using differential pulse voltammetry was established. Because AA loses its electrochemical activity after being oxidized, hydrogen peroxide was used to oxidize AA, and the interference of AA was completely eliminated. As a result, trace DA could be directly determined in the AA solution with a bare glassy carbon electrode. When trace DA was determined in a 1.0 mmol L −1 AA solution, there was a wide linear range from 3.0×10 −8 mol L −1 to 1.0×10 −5 mol L −1 . The application of this method was demonstrated by the selective measurement of DA in an injection without pretreatment.