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Poly‐(Alizarin Red S)‐Modified Glassy Carbon Electrode for Simultaneous Electrochemical Determination of Levodopa, Homovanillic Acid and Ascorbic Acid
Author(s) -
HatefiMehrjardi Abdolhamid,
Ghaemi Nasrin,
Karimi Mohammad Ali,
Ghasemi Masoumeh,
IslamiRamchahi Somaieh
Publication year - 2014
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201400302
Subject(s) - ascorbic acid , homovanillic acid , chemistry , glassy carbon , amperometry , detection limit , electrochemistry , electrode , inorganic chemistry , chromatography , nuclear chemistry , cyclic voltammetry , biochemistry , receptor , food science , serotonin
A polymeric film of Alizarin Red S was formed on a glassy carbon electrode and used for electrochemical detection of Levodopa ( L ‐DOPA) and homovanillic acid (HVA) in the presence of ascorbic acid (AA). The sensor represented excellent electrocatalytic activity for their oxidations. The resultant differential pulse voltammograms show well defined and fully resolved anodic oxidation peaks for determination of the analytes. Anodic oxidation currents of L ‐DOPA, HVA, and AA showed linearity with good correlation coefficient (>0.996), high sensitivity, and low detection limits (6, 17, and 30 nM respectively). The sensor was used for recovery of analytes in human plasma samples.