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Electrochemical Sensing of Uric Acid Using Glassy Carbon Modified with Multiwall Carbon Nanotubes Dispersed in Polyethylenimine
Author(s) -
Gutiérrez Alejandro,
Lozano Maria L.,
Galicia Laura,
Ferreyra Nancy F.,
Rivas Gustavo A.
Publication year - 2014
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201400287
Subject(s) - polyethylenimine , ascorbic acid , carbon nanotube , differential pulse voltammetry , glassy carbon , electrochemistry , materials science , carbon fibers , voltammetry , inorganic chemistry , chemistry , cyclic voltammetry , nuclear chemistry , electrode , nanotechnology , composite number , transfection , biochemistry , food science , gene , composite material
This work reports the advantages of using glassy carbon electrodes modified with multiwall carbon nanotubes (MWCNT) dispersed in polyethylenimine (PEI). The presence of MWCNTs wrapped by PEI largely facilitated the strong adsorption of uric acid (UA) and allowed its highly sensitive and selective quantification even in the presence of high excess of ascorbic acid. The selected conditions for the electrochemical sensing were 5 s accumulation at −0.300 V under stirring and quantification in a 0.050 M phosphate buffer solution pH 7.40 by differential pulse voltammetry adsorptive‐stripping after medium exchange. The platform allowed the successful application in the quantification of UA in urine.