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Electrochemical Behavior of Graphene‐Based Sensors on the Redox Mechanism of Aspirin
Author(s) -
Patil Shreekant M.,
Sataraddi Sanjeevaraddi R.,
Bagoji Atmanand M.,
Pathan Riyazkhan M.,
Nandibewoor Sharanappa T.
Publication year - 2014
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201300650
Subject(s) - graphene , aspirin , electrochemistry , redox , detection limit , materials science , differential pulse voltammetry , horizontal scan rate , electrode , peak current , analytical chemistry (journal) , chemical engineering , inorganic chemistry , chemistry , cyclic voltammetry , nanotechnology , chromatography , metallurgy , biochemistry , engineering
The electrochemical behavior of aspirin at a graphene modified glassy carbon electrode has been investigated using cyclic and differential pulse voltammetric techniques. The dependence of the current on pH, concentration and scan rate was investigated to optimize the experimental conditions for determination of aspirin. A plausible oxidation mechanism was proposed. Under the optimum conditions, the oxidation peak current was linearly proportional to the concentration of aspirin in the range from 1.00×10 −6 to 2.00×10 −4 M with a detection limit of 20.2 nM. The proposed method was successfully applied to aspirin determination in pharmaceutical and real samples.