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Disposable Solid‐State Sensor Based on Polypyrrole Films Doped for Potentiometric Determination of Dipyrone in Human Urine and Pharmaceuticals Products
Author(s) -
Bindewald Eduardo H.,
Bergamini Márcio F.,
MarcolinoJr Luiz H.
Publication year - 2013
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201300098
Subject(s) - polypyrrole , potentiometric titration , potentiometric sensor , electrochemistry , electrode , doping , materials science , matrix (chemical analysis) , linear range , chemistry , chromatography , detection limit , optoelectronics
The present manuscript describes the development of a sensitive and selective disposable solid‐state potentiometric sensor based on doped polypyrrole films (PPy) for dipyrone determination. The dipyrone was incorporated in the PPy matrix during electrochemical polymerization realized under galvanostatic conditions at a graphite pencil electrode. The sensor response for dipyrone was linear in the concentration range from 1.0×10 −4 to 4.0×10 −2 mol L −1 with a slope of 29 mV dec −1 without interference of inorganic and/or organic species. The method was successfully applied in the determination of dipyrone in spiked human urine and pharmaceutical commercial samples.