Premium
Deposition Strategies for Osmium/Enzyme Films on Gold Electrode Based Sensing Arrays
Author(s) -
McKenzie Jennifer R.,
Zhang Chengxiao,
Li ChenZhong
Publication year - 2013
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201200547
Subject(s) - analyte , glucose oxidase , biosensor , electrode , osmium , deposition (geology) , nanotechnology , materials science , electrochemistry , electrode array , chemistry , chromatography , organic chemistry , catalysis , paleontology , sediment , ruthenium , biology
Multi‐analyte real‐time interrogation of cellular activity allows for the potential discovery of novel insights into disease. In this report, the addition of electrochemical biosensors to a previously developed platform utilizing Au microfabricated electrodes was explored. Glucose oxidase was immobilized at the electrode surface with an osmium redox polymer, using hand‐casting and electrodeposition techniques, allowing for the first comparison of deposition techniques at a Au microfabricated array. This preliminary work is the first step toward the goal of creating a multi‐analyte array for cellular analysis.