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Electrochemical Study of Moroxydine and its Voltammetric Determination with a Silver Amalgam Film Electrode
Author(s) -
Skrzypek S.
Publication year - 2011
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201100343
Subject(s) - electrode , electrocatalyst , chemistry , inorganic chemistry , hanging mercury drop electrode , electrochemistry , amalgam (chemistry) , mercury (programming language) , dropping mercury electrode , voltammetry , cyclic voltammetry , adsorptive stripping voltammetry , adsorption , working electrode , organic chemistry , computer science , programming language
Abstract Moroxydine (Mor.) is an antiviral agent of biguanide structure. The paper presents a new silver amalgam film electrode (Hg(Ag)FE) for determination of Mor. in phosphate buffer, pH 6.2 ( LOD =4×10 −9 mol L −1 , LOQ = 1×10 −8 mol L −1 ) and in spiked urine using square wave adsorptive stripping voltammetry. It was found that the compound can act as an electrocatalyst not only at hanging mercury drop electrode but also at the Hg(Ag)FE. The electrode mechanism is connected with the hydrogen evolution reaction catalyzed by moroxydine. Adsorption of moroxydine at the mercury electrode was studied and special arrangements of molecules enabling electron transfer of the protonated form of moroxydine is suggested.