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Glucose Biosensor Using Glucose Oxidase and Electrospun Mn 2 O 3 ‐Ag Nanofibers
Author(s) -
Huang Shan,
Ding Yu,
Liu Yixin,
Su Liang,
Filosa Raymond,
Lei Yu
Publication year - 2011
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201100221
Subject(s) - biosensor , glucose oxidase , nanofiber , electrospinning , calcination , materials science , amperometry , selectivity , nuclear chemistry , detection limit , chemical engineering , nanotechnology , chemistry , electrochemistry , chromatography , catalysis , electrode , organic chemistry , polymer , composite material , engineering
The highly porous Mn 2 O 3 ‐Ag nanofibers were fabricated by a facile two‐step procedure (electrospinning and calcination). The structure and composition of the Mn 2 O 3 ‐Ag nanofibers were characterized by SEM, TEM, XRD, EDX and SAED. The as‐prepared Mn 2 O 3 ‐Ag nanofibers were then employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric glucose biosensor. The biosensor shows fast response to glucose, high sensitivity (40.60 µA mM −1 cm −2 ), low detection limit (1.73 µM at S / N =3), low K m,app value and excellent selectivity. These results indicate that the novel Mn 2 O 3 ‐Ag nanfibers‐GOD composite has great potential application in oxygen‐reduction based glucose biosensing.
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