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A Selective Simultaneous Determination of Levodopa and Serotonin Using a Glassy Carbon Electrode Modified with Multiwalled Carbon Nanotube/Chitosan Composite
Author(s) -
Babaei Ali,
Babazadeh M.
Publication year - 2011
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201000755
Subject(s) - chronoamperometry , differential pulse voltammetry , carbon nanotube , electrode , materials science , cyclic voltammetry , chitosan , analytical chemistry (journal) , nuclear chemistry , nanotechnology , electrochemistry , chemistry , chromatography , organic chemistry
A glassy carbon electrode (GCE) modified with carbon nanotube/chitosan (MWCNTs‐CHT/GCE) was used for the sensitive voltammetric determination of levodopa (Lev) and serotonin (Ser). The measurements were carried out using cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CA). Under the optimum conditions the electrode provides a linear response versus Lev and Ser concentrations in the range of 2.0–220.0 µM and 0.5–130.0 µM, respectively, using DPV. The modified electrode was satisfactorily used for determination of Lev and Ser in human serum and urine with satisfactory results.