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Preparation and Application of Urea Electrochemical Sensor Based on Chitosan Molecularly Imprinted Films
Author(s) -
Chen YanPing,
Liu Bin,
Lian HuiTing,
Sun XiangYing
Publication year - 2011
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201000693
Subject(s) - molecularly imprinted polymer , urea , chitosan , electrochemistry , detection limit , electrochemical gas sensor , linear range , materials science , selectivity , nuclear chemistry , chemical engineering , nanotechnology , chemistry , chromatography , electrode , organic chemistry , catalysis , engineering
A novel urea electrochemical sensor was constructed based on chitosan molecularly imprinted films which were prepared by potentiostatic electrodeposition of chitosan in the presence of urea followed by eluting with 0.1 M KCl. Various techniques were carried out to investigate the formation of molecularly imprinted polymer (MIP) films and the performance of the sensor. According to our expectation, the urea MIP electrochemical sensor showed excellent selectivity to urea among the structural similarities and co‐existences, high linear sensitivity to urea in the range from 1.0×10 −8 to 4.0×10 −5 M with a detection limit of 5.0×10 −9 M. Furthermore, the recovery ranged from 96.3 % to 103.3 % and therefore offered great potential for clinical diagnosis applications.