Premium
Electrochemical Detection of Uric Acid in Mixed and Clinical Samples: A Review
Author(s) -
Lakshmi Dhana,
Whitcombe Michael J.,
Davis Frank,
Sharma Piyush Sindhu,
Prasad Bhim Bali
Publication year - 2011
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201000525
Subject(s) - uric acid , analyte , nanotechnology , electrochemistry , conductive polymer , materials science , polymer , chemistry , chromatography , organic chemistry , biochemistry , electrode
The present review has sought to explore the technological advances that have been made in recent years towards the selective analysis of uric acid and critically evaluate how they could, in fact, be exploited as a basis for a multi analyte sensor incorporating uric acid detection. Numerous strategies have evolved in recent years but these have invariably focused on the manufacture and response characterization of discrete sensors. Various methods of obtaining selective detection such as use of uricase enzymes, nanoparticles, carbon nanotubes, polymers, conducting polymers and MIPs are also discussed along with the clinical relevance of UA determination.