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Design of a Vitamin B 1 ‐Selective Electrode Based on an Ion‐Pair and Its Application to Pharmaceutical Analysis
Author(s) -
Antal Iryna,
Kormosh Zholt,
Bazel Yaroslav,
Lysenko Svitlana,
Kormosh Natalya
Publication year - 2010
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201000124
Subject(s) - potentiometric titration , electrode , chemistry , ion , titration , multivitamin , ion selective electrode , glass electrode , working electrode , inorganic chemistry , analytical chemistry (journal) , vitamin , chromatography , electrochemistry , organic chemistry , catalysis , selectivity , biochemistry
Vitamin B 1 ‐selective electrodes with PVC membrane were developed that contain ion associates of vitamin B 1 with an inorganic anion, BiI 4 − , and an organic anion, brilliant yellow, as electrode‐active substances. The linearity ranges of the electrode function are 1.0×10 −5 –1.0×10 −2 and 1.0×10 −4 –1.0×10 −2 M, the electrode function slopes are 33.0±1.0 and 33.1±1.1 mV decade −1 , the detection limits are 5.5×10 −6 and 8.3×10 −5 M for BiI 4 − and brilliant yellow respectively. The working range of pH is 5–12. The efficiency of the use of electrodes for the vitamin B 1 content control in multivitamin pharmaceutical preparations was shown by direct potentiometry and potentiometric titration methods.