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Carbon Nanotubes‐Ionic Liquid and Chloropromazine Modified Electrode for Determination of NADH and Fabrication of Ethanol Biosensor
Author(s) -
Salimi Abdollah,
Lasghari Saied,
Noorbakhash Abdollah
Publication year - 2010
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.201000020
Subject(s) - differential pulse voltammetry , detection limit , biosensor , ionic liquid , alcohol dehydrogenase , electrode , carbon nanotube , chemistry , cyclic voltammetry , voltammetry , adsorption , redox , nanocomposite , inorganic chemistry , ethanol , materials science , electrochemistry , chromatography , nanotechnology , organic chemistry , catalysis
Potential cycling was used for oxidation of chloropromazine and producing an electroactive redox couples which strongly adsorbed on the electrode surface modified with carbon nanotubes and ionic liquid nanocomposite. The modified electrode shows excellent electrocatalytic activity toward NADH oxidation. The differential pulse voltammetry detection provided high sensitivity, 0.5835 A M −1 , low detection limit, 80 nM at concentration range up to 20 μM. An ethanol biosensor was also developed by immobilizing alcohol dehydrogenase enzyme onto nanocomposite. Differential pulse voltammetric detection of ethanol gives linear responses over the concentration range 40 μM–1.5 mM with detection limit 5 μM and sensitivity 1.97 μA mM −1 .