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Glassy Carbon Paste Electrodes for the Determination of Fructosyl Valine
Author(s) -
Chien HuiChing,
Chou TseChuan
Publication year - 2010
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200900384
Subject(s) - valine , amperometry , glassy carbon , detection limit , correlation coefficient , hemoglobin , chemistry , carbon fibers , electrode , analytical chemistry (journal) , chromatography , materials science , electrochemistry , mathematics , organic chemistry , biochemistry , amino acid , cyclic voltammetry , statistics , composite material , composite number
Nearly 200 million people worldwide have type‐2 diabetes. Glucose sensors are routinely used for diagnosis; however, the relative amount of glycosylated hemoglobin (HbA1c) may be a better marker. A working electrode made from bare glassy carbon paste was used for sensing fructosyl valine (Fru‐Val), a component of HbA1c. Amperometric measurements revealed a linear relationship between Fru‐Val concentration and the sensing current. The square correlation coefficient and the sensitivity were 0.999 and 5.26 μA mM −1 , respectively. The minimum detection limit was less than 0.05 mM.
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