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One‐Step Electrochemically Deposited Nanocomposite Film of CS‐Fc/MWNTs/GOD for Glucose Biosensor Application
Author(s) -
Liang RuPing,
Fan LiXia,
Wang Rui,
Qiu JianDing
Publication year - 2009
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200804596
Subject(s) - biosensor , glucose oxidase , biocomposite , nanocomposite , biomolecule , ferrocene , materials science , nanotechnology , bioelectronics , chitosan , electrochemistry , carbon nanotube , electrode , chemical engineering , biocompatibility , chemistry , composite number , composite material , engineering , metallurgy
A simple and controllable electrodeposition approach was proposed for one‐step construction of glucose biosensors by in situ co‐deposition of ferrocene‐branched chitosan derivatives (CS‐Fc), multiwalled carbon nanotubes (MWNTs), and glucose oxidase (GOD) onto electrode surface. The formation of CS‐Fc could not only effectively prevent the leakage of Fc and retain its electrochemical activity, but also provide a biocompatible microenvironment for retaining the native activity of the immobilized biomolecules. Further entrapment of MWNTs into the CS matrix improved electronic conductivity of the biocomposite significantly. The facile procedure of immobilizing GOD and the promising feature of biocomposite will offer a versatile platform to fabricate biosensors and bioelectronic devices.