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Study on Sensitization from Reactive Oxygen Species for Electrochemiluminescence of Luminol in Neutral Medium
Author(s) -
Chu Haihong,
Guo Wenying,
Di Junwei,
Wu Ying,
Tu Yifeng
Publication year - 2009
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200804580
Subject(s) - luminol , electrochemiluminescence , sensitization , chemistry , chemiluminescence , biomolecule , oxygen , photochemistry , environmental chemistry , chromatography , detection limit , organic chemistry , biochemistry , biology , immunology
In this paper, the sensitization on electrochemiluminescent (ECL) reaction of luminol from reactive oxygen species (ROSs) in neutral medium was studied. The powerful sensitization from ROSs even related with organics and organisms were examined under selected conditions which were suitable for biochemical analysis. The results indicated that whether the enhancers were dissolved in solutions or immobilized on the surface of conventional electrodes, stronger ECL intensity of luminol could be obtained. Enhanced ECL helped to provide groundwork for the detection of biomolecules for which would further enhance or quench the ECL signals. The technique may provide new means in a variety of fields such as clinical diagnostics, immunological analysis and environmental monitoring due to its simplicity and high efficiency.