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Hemoglobin‐Titanate Composite Based Biosensor for the Amperometric Determination of Hydrogen Peroxide in Acidic Medium
Author(s) -
Wu Yihua,
Gao Qiuming,
Shi Linpu,
Gao Lu
Publication year - 2009
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200804520
Subject(s) - pyrolytic carbon , hydrogen peroxide , biosensor , detection limit , electrode , amperometry , buffer solution , composite number , titanate , chemistry , redox , buffer (optical fiber) , inorganic chemistry , electrochemistry , materials science , nuclear chemistry , chromatography , nanotechnology , pyrolysis , organic chemistry , ceramic , composite material , telecommunications , computer science
A hemoglobin‐titanate composite based biosensor was chosen for determination of H 2 O 2 in an acidic medium. CV results of the Hb‐titanate modified pyrolytic graphite electrode showed a pair of well‐defined, quasi‐reversible redox peaks centered at −246 mV (vs. Ag/AgCl) in a pH 5.0 HAc‐NaAc buffer solution. The modified electrode exhibited good electrocatalytic response for monitoring H 2 O 2 and had a large linear detection range from 20 μM to 3.2 mM with a detection limit of 8 μM ( S / N =3) and a sensitivity of 29.7 mA M −1 cm −2 in the pH 5.0 solution. The biosensor also possessed good long term storage stability.