Premium
Sm 3+ Potentiometric Membrane Sensor as a Probe for Determination of Some Pharmaceutics
Author(s) -
Ganjali Mohammad Reza,
Memari Zahra,
Faridbod Farnoush,
Dinarvand Rassoul,
Norouzi Parviz
Publication year - 2008
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200804374
Subject(s) - potentiometric titration , sodium tetraphenylborate , potentiometric sensor , detection limit , membrane , chemistry , ion selective electrode , ionophore , samarium , inorganic chemistry , dibutyl phthalate , polyvinyl chloride , pharmaceutics , plasticizer , nuclear chemistry , chromatography , ion , selectivity , organic chemistry , biochemistry , catalysis , medicine , pharmacology
The increase use of ion sensors in the fields of environmental, agricultural, and medical analysis is stimulating analytical chemists to develop new sensors for fast, accurate, reproducible, and selective determination of various ions. In this study a new samarium membrane sensor was constructed and for the first time, it was applied as a probe in indirect determination of hyoscine, homatropine, and tramadol drugs in their pharmaceutical formulation. The proposed membrane sensor was constructed based on a membrane containing 2% sodium tetraphenyl borate (NaTPB) as an anionic additive, 63% dibutyl phthalate (DBP) as solvent mediator, 5% ionophore, and 30% poly(vinyl chloride) (PVC). The proposed Sm(III) electrode exhibits a Nernstian response of 19.35±0.2 mV per decade of samarium concentration, and has a lower detection limit of 1.0×10 −7 M. The linear range of the sensors was 1.0×10 −7 –1.0×10 −1 M. It works well in the pH range of 3.0–8.0.