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Direct Electron Transfer and Electrocatalysis of Hemoglobin on Chitosan‐TiO 2 Nanorods‐Glass Carbon Electrode
Author(s) -
Xiao Xiaoling,
Lu Wu,
Yao Xin
Publication year - 2008
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200804319
Subject(s) - nanorod , chitosan , electrocatalyst , electron transfer , electrochemistry , electrode , biopolymer , materials science , redox , glassy carbon , biosensor , composite number , chemical engineering , carbon fibers , nanotechnology , chemistry , photochemistry , cyclic voltammetry , composite material , polymer , engineering , metallurgy
The direct electron transfer between hemoglobin (Hb) and the glassy carbon electrode (GC) can be readily achieved via a high biocompatible composite system based on biopolymer chitosan (CHT) and TiO 2 nanorods (TiO 2 ‐NRs). TiO 2 ‐NRs greatly promote the electron transfer between Hb and GC, which contribute to the higher redox peaks. UV‐vis spectra result indicated the Hb entrapped in the composite film well keep its native structure. The immobilized Hb remains its bioelectrocatalytical activity to the reduction of H 2 O 2 with a lower detection limit. A novel, sensitive, reproducible and stable electrochemical biosensing platform of H 2 O 2 based on Hb‐TiO 2 ‐CHT electrode is explored.