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Electrocatalytic Application of an Overoxidized Dopamine Film Prepared on a Gold Electrode Surface to Selective Epinephrine Sensing
Author(s) -
Łuczak Teresa
Publication year - 2008
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200704181
Subject(s) - epinephrine , detection limit , electrode , ascorbic acid , dopamine , electrochemistry , phosphate buffered saline , materials science , chemistry , inorganic chemistry , chromatography , anesthesia , neuroscience , biology , medicine , food science
A dopamine polymer film was prepared ex situ on a bare gold template from a 10 mM dopamine solution in phosphate buffer, pH 7 followed by an overoxidation in 500 mM NaOH. The modified electrode was used for quantitative determination of epinephrine. A linear relationship between epinephrine concentration and current response was obtained in the range between 2 μM and 800 μM with the detection limit of 0.3 μM. The results have shown that using the overoxidized dopamine film it is possible to perform electrochemical analysis of epinephrine without interference of ascorbic and uric acids.