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Direct Electrochemistry of Cytochrome c on a Silica Sol‐Gel Film Modified Electrode
Author(s) -
Xu JunSheng,
Zhao GuangChao
Publication year - 2008
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200704164
Subject(s) - cyclic voltammetry , electrode , electrochemistry , chemically modified electrode , inorganic chemistry , redox , adsorption , cytochrome c , sol gel , aqueous solution , silica gel , chemistry , materials science , buffer solution , voltammetry , working electrode , chromatography , nanotechnology , organic chemistry , biochemistry , mitochondrion
Dilute silica sol‐gel was simply dropped on the surface of a basal plane graphite electrode (BPGE) to form a silica sol‐gel film modified electrode. Direct electrochemical response of cytochrome c (Cyt c) on the modified electrode was observed by cyclic voltammetry (CV). The results suggested that Cyt c could be tightly adsorbed on the surface of the silica sol‐gel film modified electrode. A couple of well‐defined and nearly reversible redox peaks can be observed in a phosphate buffer solution (pH 7.0), which anodic and cathodic peak potentials were at −0.243 and −0.306 V (vs. Ag/AgCl), respectively. Cyt c adsorbed on the surface of silica sol‐gel film shows a remarkable electrocatalytic activity for the reduction of oxygen. Based on these, a third‐generation biosensor could be constructed to detect the concentration of oxygen in aqueous solution.