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Organically Modified Sol‐Gel/Chitosan Composite Based Glucose Biosensor
Author(s) -
Chen Xu,
Jia Jianbo,
Dong Shaojun
Publication year - 2003
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200390076
Subject(s) - biosensor , chronoamperometry , chitosan , cyclic voltammetry , biocompatibility , immobilized enzyme , glucose oxidase , ferrocene , chemistry , electrode , materials science , chromatography , chemical engineering , nanotechnology , electrochemistry , enzyme , organic chemistry , engineering
A new type of organically modified sol‐gel/chitosan composite material was developed and used for the construction of glucose biosensor. This material provided good biocompatibility and the stabilizing microenvironment around the enzyme. Ferrocene was immobilized on the surface of glassy carbon electrode as a mediator. The characteristics of the biosensor were studied by cyclic voltammetry and chronoamperometry. The effects of enzyme‐loading, buffer pH, applied potential and several interferences on the response of the enzyme electrode were investigated. The simple and low‐cost glucose biosensor exhibited high sensitivity and good stability.