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Disposable Carbon Nanotube Modified Screen‐Printed Biosensor for Amperometric Detection of Organophosphorus Pesticides and Nerve Agents
Author(s) -
Lin Yuehe,
Lu Fang,
Wang Joseph
Publication year - 2004
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200302933
Subject(s) - choline oxidase , biosensor , carbon nanotube , hydrogen peroxide , amperometry , chemistry , detection limit , substrate (aquarium) , glucose oxidase , nanotechnology , nerve agent , chromatography , materials science , acetylcholinesterase , organic chemistry , enzyme , electrochemistry , biochemistry , electrode , oceanography , geology
A disposable carbon nanotube‐based biosensor was successfully developed and applied to the detection of organophosphorus (OP) pesticides and nerve agents. The biosensors using acetycholinesterase (AChE)/choline oxidase (CHO) enzymes provided a high sensitivity, large linear range, and low detection limits for the analysis of OP compounds. Such characteristics may be attributed to the catalytic activity of carbon nanotube to promote the redox reaction of hydrogen peroxide produced during AChE/CHO enzymatic reactions with their substrate, as well as the large surface area of carbon nanotube materials.