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Selective Determination of Uric Acid in Presence of Ascorbic Acid and Dopamine at Neutral pH Using Exfoliated Graphite Electrodes
Author(s) -
Ramesh P.,
Sampath S.
Publication year - 2004
Publication title -
electroanalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 128
eISSN - 1521-4109
pISSN - 1040-0397
DOI - 10.1002/elan.200302890
Subject(s) - ascorbic acid , uric acid , chemistry , graphite , detection limit , electrode , dopamine , adsorption , inorganic chemistry , chromatography , nuclear chemistry , biochemistry , organic chemistry , medicine , food science
Abstract Exfoliated graphite electrodes have been used to detect uric acid at neutral pHs, by following its oxidation. A linear range of 5–53 μM and a detection limit of 5 μM are observed at a pH of 7.0. Uric acid was found to be selectively adsorbed on exfoliated graphite surface in the presence of excess ascorbic acid. This leads to its selective determination in the presence of ascorbic acid. Simultaneous detection of uric acid, dopamine and ascorbic acid has also been demonstrated on exfoliated graphite electrodes in a pH 7 buffer.